Article SCIELO SCOPUS
Journal of the Chilean Chemical Society  (2006)

SYNTHESIS AND CONFORMATIONAL ANALYSIS OF LEPTOCARPIN DERIVATIVES: INFLUENCE OF MODIFICATION OF THE OXIRANE RINGON LEPTOCARPIN'S CYTOTOXIC ACTIVITY

MARTÍNEZ, ROLANDO; Kesternich, Victor; CARRACSO, HÉCTOR; ÁLVAREZ-CONTRERAS, CAROLINA; Montenegro, Carolina; Ugarte, Ricardo; Gutierrez, Elena; Moreno, Jose; García Carlos; Werner, Enrique; CÁRCAMOS, JUAN

Abstract

The reaction in acidconditions of Leptocarpin 1, a compound with antitumor activity, formed two new isomeric products, 8b-angeloyl-1b,3b-dihydroxy-4,10-dimethyl,-D11(13) methylen-4Z,9Z-dieneheliangol-6,12-olide 2 and 8b-angeloyl-1b,3b-dihydroxy-4-methyl-D11(13),D11(14)-dimethylen-4Z-eneheliangol-6,12-olide 3, whose structures reported in this study were established by spectroscopy (

Más información

Título según SCOPUS: Synthesis and conformational analysis of leptocarpin derivatives. Influence of modification of the oxirane ringon leptocarpin's cytotoxic activity
Título según SCIELO: SYNTHESIS AND CONFORMATIONAL ANALYSIS OF LEPTOCARPIN DERIVATIVES: INFLUENCE OF MODIFICATION OF THE OXIRANE RINGON LEPTOCARPIN'S CYTOTOXIC ACTIVITY
Título de la Revista: Journal of the Chilean Chemical Society
Volumen: 51
Número: 4
Editorial: SOC CHILENA QUIMICA
Fecha de publicación: 2006
Página de inicio: 1010
Página final: 1014
Idioma: en
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072006000400003&lng=en&nrm=iso&tlng=en
DOI:

10.4067/S0717-97072006000400003
Notas: SCIELO, SCOPUS