Granulomatosis sarcoidea necrosante con compromiso sistémico

Ceballos, María Elena; Hormazábal F, José; Torres, Carmen; OYONARTE W, MAITE; Rodríguez D, Juan Carlos; Meneses, Manuel; Chernilo S, Sara

Keywords: vasculitis, Arteritis, Sarcoid, necrotizing granulomatosis, granulomatosis sarcoidea necrosante

Abstract

A 70-year-old mapuche female presented with a 1 year history of weight loss, bilateral red painful eyes and corneal ulcer that evolved into perforation and uveal herniation with complete visual loss. Reddish and painful nodules appeared on the distal aspect of both lower extremities, that ulcerated after months. A thoracic CT scan showed multiple pulmonary nodules. Infectious diseases were ruled out. An open lung biopsy and a skin biopsy were performed and both showed non-caseating necrotizing granulomas and granulomatous arteritis. Steroids and cyclophosphamide were started with complete regression of skin and pulmonary lesions within a month. Corneal transplantation was done. After 6 months follow-up, the patient is on low-dose of steroids, free of disease with partial vision recovery

Más información

Título según SCIELO: Granulomatosis sarcoidea necrosante con compromiso sistémico
Título de la Revista: REVISTA CHILENA DE ENFERMEDADES RESPIRATORIAS
Volumen: 22
Número: 3
Editorial: Sociedad Chilena de Enfermedades Respiratorias
Fecha de publicación: 2006
Página de inicio: 191
Página final: 195
Idioma: es
DOI:

10.4067/S0717-73482006000300008

Notas: SCIELO