Abstract

"Post infectious obliterans bronchiolitis (OB) causes persistent pulmonary function impairment and could affect patient ability to perform exercise. Six minute-walk test (6MWT) is a useful tool to study these aspects. Objective: Children with OB were evaluated with spirometry and 6MWT and the relationship between spirometrics measurements and 6MWT were determined. Twenty-seven children with OB were studied with a base line spirometry and 6MWT. Correlation between spirometry and 6MWT: covered distance, Borg index (BI), oxygen saturation (0(2)S) and heart rate (HR), were carried out using Rho of Spearman with SPSS 11.5. There was not relation between the covered distance and spirometrics values; only FVC correlates with final 0(2)S (rho = 0.4; p = 0.02). The other spirometrics variables correlates with BI, 0(2)S andHR; Interestingly FEV1correlates with: BI (rho = -0.7; p < 0.01), 0(2)S (rho = 0.5; p < 0.01) and HR (rho = -0.5; p < 0.01). BI was significant related to FEV1/FVC (rho = -0.7; p < 0.01) and FEF25-75 (rho = -0.8; p < 0.01). Airflow obstruction, especifically a low FEV1 is related with a high BI and HR; and also with a lower 0(2)S at the end of6MWT Increase ofBI is the change most related with airflow obstruction."