Article ISI SCOPUS
DIABETES RESEARCH AND CLINICAL PRACTICE  (2009)

Associations of the CTLA-4 polymorphisms with type 1 diabetes in a Chilean population: Case-parent design

Ángel B.; Balic, I; Santos, JL; Codner, E; Carrasco, E; Perez-Bravo, F

Abstract

CTLA-4 plays a key role in T cells regulation. We analysed the CTLA-4 +49A/G and -318C/T polymorphisms in 178 cases of type 1 diabetes and their parents (534 individuals) from Santiago, Chile. A significant overall association with T1D (p = 0.028) was observed, possibly due to an overtransmission of the G-T haplotype. © 2009 Elsevier Ireland Ltd. All rights reserved.

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Título según WOS: Associations of the CTLA-4 polymorphisms with type 1 diabetes in a Chilean population: Case-parent design
Título según SCOPUS: Associations of the CTLA-4 polymorphisms with type 1 diabetes in a Chilean population: Case-parent design
Título de la Revista: DIABETES RESEARCH AND CLINICAL PRACTICE
Volumen: 85
Número: 3
Editorial: ELSEVIER IRELAND LTD
Fecha de publicación: 2009
Página de inicio: E34
Página final: E36
Idioma: English
DOI:

10.1016/j.diabres.2009.05.019
Notas: ISI, SCOPUS