Synthesis, characterization, and crystal structure of 2 ',2 ''-dihydroxy-3,3 '''-bichalcone and its related chalcone-flavanone and biflavanone analogs

Escobar, CA; Fernandez, WA; Trujillo A.; Santos, JC; Roisnel T.; Fuentealba, M

Abstract

The synthesis of 3,3'-diformyl-1,1'-biphenyl 1 and its reaction in basic media with 2'-hydroxyacetophenone and paeonol, respectively, are described. The products, a bichalcone 2, it's partially cyclized analog, a flavanone-chalcone 3 and the fully cyclized biflavanone 4, are reported as products for the first reaction, while only the chalcone 5 for the second. The crystalline and molecular structure, solved by X-ray diffraction analysis, for compounds 2 and 5 are also presented in this work. (C) 2014 Elsevier Ltd. All rights reserved.

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Título según WOS: Synthesis, characterization, and crystal structure of 2 ',2 ''-dihydroxy-3,3 '''-bichalcone and its related chalcone-flavanone and biflavanone analogs
Título según SCOPUS: Synthesis, characterization, and crystal structure of 2?,2?-dihydroxy-3,3?-bichalcone and its related chalcone-flavanone and biflavanone analogs
Título de la Revista: TETRAHEDRON LETTERS
Volumen: 55
Número: 38
Editorial: PERGAMON-ELSEVIER SCIENCE LTD
Fecha de publicación: 2014
Página de inicio: 5271
Página final: 5274
Idioma: English
DOI:

10.1016/j.tetlet.2014.07.111

Notas: ISI, SCOPUS