Common Ground: Stem Cell Approaches Find Shared Pathways Underlying ALS

Matus, S; Medinas DB; hetz C.

Abstract

The development of curative therapies for genetically complex diseases such as ALS has been delayed by the lack of relevant disease models. Recent advances using induced-pluripotent-stem-cell-derived motoneurons from patients harboring distinct ALS mutations have recapitulated essential disease features and have identified some common pathways driving disease pathogenesis.

Más información

Título según WOS: Common Ground: Stem Cell Approaches Find Shared Pathways Underlying ALS
Título según SCOPUS: Common ground: Stem cell approaches find shared pathways underlying ALS
Título de la Revista: CELL STEM CELL
Volumen: 14
Número: 6
Editorial: Cell Press
Fecha de publicación: 2014
Página de inicio: 697
Página final: 699
Idioma: English
DOI:

10.1016/j.stem.2014.05.001

Notas: ISI, SCOPUS