Portal del Investigador
A Novel ER Stress-Independent Function of the UPR in Angiogenesis
Abstract
Tumors rely on the unfolded protein response (UPR) and angiogenesis to survive the metabolic stress of hypoxia. Karali et al. (2014) revealed that VEGF signaling engages UPR sensors in an unconventional manner that is independent of endoplasmic reticulum (ER) stress, mediated by mTOR signaling to promote endothelial cell survival and angiogenesis.
Más información
| Título según WOS: | A Novel ER Stress-Independent Function of the UPR in Angiogenesis |
| Título según SCOPUS: | A Novel ER Stress-Independent Function of the UPR in Angiogenesis |
| Título de la Revista: | MOLECULAR CELL |
| Volumen: | 54 |
| Número: | 4 |
| Editorial: | Cell Press |
| Fecha de publicación: | 2014 |
| Página de inicio: | 542 |
| Página final: | 544 |
| Idioma: | English |
| DOI: |
10.1016/j.molcel.2014.05.013 |
| Notas: | ISI, SCOPUS |