Abstract

Objective: To identify factors associated with non-compliance to antidepressant's (AD) treatment in Santiago, Chile. Methods: A cross-sectional study was carried out in a household randomized and representative sample of 1000 individuals aged 15 years and older. Treatment adherence was studied in AD consumers using logistic regression to estimate factors associated with non-compliance in doses or time of treatment. Results: Antidepressant non-compliance was 52.8% and their main associated factor was income. Gender and educational level were also associated with AD non-compliance. Conclusions: Antidepressant non-compliance was associated with income and sociodemographic characteristics in Chilean patients. Therefore, health strategies to improve AD compliance should consider inequities in access to medications and characteristics of the AD consumers. © 2011 International Society for Pharmacoeconomics and Outcomes Research (ISPOR).