Highly Efficient Potentiometric Glucose Biosensor Based on Functionalized InN Quantum Dots

Alvi, N. H.; Soto Rodriguez, P. E. D.; Gómez, V. J.; Kumar, P.; Amin, G.; Nur, O.; Willander, M.; Nötzel, R.

Abstract

We present a fast, highly sensitive, and efficient potentiometric glucose biosensor based on functionalized InN quantum-dots (QDs). The InN QDs are grown by molecular beam epitaxy. The InN QDs are bio-chemically functionalized through physical adsorption of glucose oxidase (GOD). GOD enzyme-coated InN QDs based biosensor exhibits excellent linear glucose concentration dependent electrochemical response against an Ag/AgCl reference electrode over a wide logarithmic glucose concentration range (1 × 10−5 M to 1 × 10−2 M) with a high sensitivity of 80 mV/decade. It exhibits a fast response time of less than 2 s with good stability and reusability and shows negligible response to common interferents such as ascorbic acid and uric acid. The fabricated biosensor has full potential to be an attractive candidate for blood sugar concentration detection in clinical diagnoses.

Más información

Título de la Revista: APPLIED PHYSICS LETTERS
Volumen: 101
Número: 15
Editorial: AMER INST PHYSICS
Fecha de publicación: 2012
Página de inicio: 153110