Ch.7: “Epigenetics and arterial hypertension: evidences and perspectives”.

Simonetta Friso*, Cristian Carvajal* et al. (*equal contribution); Jeffrey Lawrence

Abstract

Key Concepts 1. The current knowledge on the link between epigenetic marks and AH is promising but yet to be deepen, potentially leading toward novel implications in AH preventive and therapeutic strategies. 2. Epigenetic changes in DNA refer to DNA methylation and hydroxymethylation, posttranslational regulation by histone modifications, and noncoding RNAs. 3. Differently from genetic features of DNA, epigenetic changes are potentially reversible by environmental/nutritional factors, and therefore of special interest for multifactorial diseases such as arterial hypertension (AH).

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Editorial: Elsevier
Fecha de publicación: 2017
Página de inicio: 159
Página final: 184
Idioma: English