Dendritic structure of single hippocampal neurons according to sex and hemisphere of origin in middle-aged and elderly human subjects

Barrera A.; Jiménez L.; Gonzalez, GM; Montiel, J; Aboitiz F.

Abstract

The organization of basilar dendritic patterns in the CA1 hippocampal region obtained from 13 middled-aged and elderly human subjects was assessed using the Golgi method. Neurons were classified according to hemisphere of origin and the sex of the respective subjects. Three parameters were measured: total dendritic length (TDL), number of dendritic segments (NDS) and average segment length (ASL, which is TDL divided by NDS). Dendritic segments were classified into proximal (first to third order) and distal (fourth order and above). Sex differences were found in distal TDL and in proximal and distal NDS, neurons belonging to males having larger values than those belonging to females. In addition, a hemispheric difference was detected in distal TDL, in which neurons of the left hemisphere had larger values than those of the right hemisphere. © 2001 Elsevier Science B.V.

Más información

Título según WOS: Dendritic structure of single hippocampal neurons according to sex and hemisphere of origin in middle-aged and elderly human subjects
Título según SCOPUS: Dendritic structure of single hippocampal neurons according to sex and hemisphere of origin in middle-aged and elderly human subjects
Título de la Revista: BRAIN RESEARCH
Volumen: 906
Número: 01-feb
Editorial: ELSEVIER SCIENCE BV
Fecha de publicación: 2001
Página de inicio: 31
Página final: 37
Idioma: English
URL: http://linkinghub.elsevier.com/retrieve/pii/S0006899301025495
DOI:

10.1016/S0006-8993(01)02549-5

Notas: ISI, SCOPUS