Mastocitosis sistémica: Caso clínico

Mardones, Pedro, Moyano Carlos, Peña, Karina, Quijada, Cesar

Abstract

We report a 38 years old female who, since her childhood, had a history of precisely limited, fixed maculo papular dark brown cutaneous lesions in the trunk and extremities. These lesions become erythematous or urticarial after rubbing, medication intake or scratching. She also had frequent episodes of tachycardia, flushing, headache, abdominal pain, arthralgia, diarrhea and vomiting. She was hospitalized in three occasions due to high frequency tachycardia, hypotension, generalized urticarial erythema and clouding of consciousness. Three of these episodes occurred after the ingestion of antiinflammatory drugs or acetylsalicylic acid. Mastocyte infiltration was confirmed in skin and bone marrow biopsies and in bone scintiscan. The use of H1, H2 blockers and mastocyte stabilizers gave partial relief to the patient.

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Título de la Revista: REVISTA MEDICA DE CHILE
Volumen: 126
Número: 7
Editorial: Sociedad Médica de Santiago
Fecha de publicación: 1998
Página de inicio: 823
Página final: 827
Idioma: English