Portal del Investigador
Natural and hemisynthetic drimane sesquiterpenoids, inhibitors of nicotinic acetylcholine receptors. Looking for behavioral modulators.
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| Fecha de publicación: | 2018 |
| Año de Inicio/Término: | 2018-2020 |
| Financiamiento/Sponsor: | FONDECYT INICIACION. |
| DOI: |
FONDECYT INICIACION. 11181076 |
| Notas: | Drimys winteri have drimane sesquiterpenoids which have been shown to be inhibitors of hα4β2 with more selectivity than hα3β4 and hα7 nAChR subtypes. nAChRs may be involved in neurological and mental dysfunctions including drug addictions, depression. We propose the isolation of natural drimanes (mu |