Copula based flexible modeling of associations between clustered event times

Geerdens, Candida; Janssen, Paul

Abstract

Multivariate survival data are characterized by the presence of correlation between event times within the same cluster. First, we build multi-dimensional copulas with flexible and possibly symmetric dependence structures for such data. In particular, clustered right-censored survival data are modeled using mixtures of max-infinitely divisible bivariate copulas. Second, these copulas are fit by a likelihood approach where the vast amount of copula derivatives present in the likelihood is approximated by finite differences. Third, we formulate conditions for clustered right-censored survival data under which an information criterion for model selection is either weakly consistent or consistent. Several of the familiar selection criteria are included. A set of four-dimensional data on time-to-mastitis is used to demonstrate the developed methodology.

Más información

Título según WOS: ID WOS:000384534100003 Not found in local WOS DB
Título de la Revista: LIFETIME DATA ANALYSIS
Volumen: 22
Número: 3
Editorial: Springer
Fecha de publicación: 2016
Página de inicio: 363
Página final: 381
DOI:

10.1007/s10985-015-9336-x

Notas: ISI