Copula based flexible modeling of associations between clustered event times
Abstract
Multivariate survival data are characterized by the presence of correlation between event times within the same cluster. First, we build multi-dimensional copulas with flexible and possibly symmetric dependence structures for such data. In particular, clustered right-censored survival data are modeled using mixtures of max-infinitely divisible bivariate copulas. Second, these copulas are fit by a likelihood approach where the vast amount of copula derivatives present in the likelihood is approximated by finite differences. Third, we formulate conditions for clustered right-censored survival data under which an information criterion for model selection is either weakly consistent or consistent. Several of the familiar selection criteria are included. A set of four-dimensional data on time-to-mastitis is used to demonstrate the developed methodology.
Más información
| Título según WOS: | ID WOS:000384534100003 Not found in local WOS DB |
| Título de la Revista: | LIFETIME DATA ANALYSIS |
| Volumen: | 22 |
| Número: | 3 |
| Editorial: | Springer |
| Fecha de publicación: | 2016 |
| Página de inicio: | 363 |
| Página final: | 381 |
| DOI: |
10.1007/s10985-015-9336-x |
| Notas: | ISI |