Article
JOURNAL OF THE CHILEAN CHEMICAL SOCIETY  (2017)

SECONDARY METABOLITES FROM PACHYSTROMA LONGIFOLIUM (NEES) I. M. JOHNST (EUPHORBIACEAE) AND EVALUATION OF ITS EXTRACTS AS CATHEPSINS INHIBITORS

GALVAO, D. C.; MORAES, C. T.; BORGES, B. J. P.; CARDOSO, W. C.; DE ANDRADE, JEAN PAULO; TAKAHASHI, P. M.; VIEIRA, P. C.; BORGES, WARLEY

Keywords: secondary metabolites, Cathepsins, Pachystroma longifolium

Abstract

In this work, four secondary metabolites were isolated from leaves of Pachystroma longifolium (Euphorbiaceae): loliolide, gallic acid, methyl protocatechuate and ethyl gallate. Their structures were established by physical and spectroscopic methods. The extracts of P. longifolium and the purifed compounds were tested as cathepsins inhibitors and the extracts were active.

Más información

Título de la Revista: JOURNAL OF THE CHILEAN CHEMICAL SOCIETY
Volumen: 62
Número: 3
Editorial: 2013
Fecha de publicación: 2017
Página de inicio: 3602
Página final: 3604
Idioma: English