Analysis of Bioactive Amaryllidaceae Alkaloid Profiles in Lycoris Species by GC-MS

GUO, Y.; PIGNI, NATALIA BELÉN; ZHENG, Y.; DE ANDRADE, JEAN PAULO; TORRAS-CLAVERIA, LAURA; BORGES, W. S.; VILADOMAT, FRANCESC; CODINA, CARLES; BASTIDA, JAUME

Keywords: amaryllidaceae alkaloids, gc-ms, lycorine, Lycoris, Galanthamine

Abstract

The genus Lycoris, a group of Amaryllidaceae plants distributed in temperate regions of Eastern Asia, is already known for containing representative alkaloids typical of this botanical family with a wide range of biological activities (for example, lycorine and galanthamine). In the present work, the alkaloid profiles of nine species, L. albiflora, L. aurea, L. chinensis, L. haywardii, L. incarnata, L. longituba, L. radiata, L. sprengeri, and L. squamigera, and one variety (L. radiata var. pumila) have been evaluated by GC-MS. Structures belonging to the lycorine-, homolycorine-, haemanthamine-, narciclasine-, tazettine-, montanine- and galanthamine-series were identified and quantified, with galanthamine- and lycorine-type alkaloids predominating and usually showing a high relative abundance in comparison with other alkaloids of the extracts. Interestingly, L. longituba revealed itself to be a potential commercial source of bioactive alkaloids. In general terms, our results are consistent with the alkaloid profiles reported in the literature for previously studied species.

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Título de la Revista: NATURAL PRODUCT COMMUNICATIONS
Volumen: 9
Número: 8
Editorial: Sage
Fecha de publicación: 2014
Página de inicio: 1081
Página final: 1086
Idioma: English