Fatal nosocomial hemorrhagic enterocolitis probably caused by adenovirus. Report of one case

Alberto Fica; Pabla Cataldo; Diana Aceituno; María Ignacia Villarroel; Arturo Escalona

Keywords: enterocolitis, cross infection, adrenal cortex hormones, adenoviridae, acute kidney injury, corticoesteroides, Lesión renal aguda

Abstract

Adenovirus (ADV) is a recognized cause of severe disease among immunocompromised patients. We report a previously healthy 39-year-old female, admitted with influenza pneumonia and evolving with lung hemorrhage and acute renal failure requiring mechanical ventilation and hemo dialysis. She received high corticosteroid doses due to an initial suspicion of alveolar hemorrhage. Lymphopenia already present before steroid use (567/mu L), was maintained during the whole hospital stay (mean 782/mu L). From the second week of admission she presented a high-volume diarrhea (mean 2.5 L/day) associated to intermittent bloody stools. An ulcerative enterocolitis was confirmed by CT images and colonoscopy. ADV was detected in a colonic tissue sample by real time PCR but not by a commercial filmarray test. Cidofovir-probenecid and racecadotril therapy were indicated without changing the clinical course of diarrhea and the patient finally died.

Más información

Título según WOS: Fatal nosocomial hemorrhagic enterocolitis probably caused by adenovirus. Report of one case
Título según SCOPUS: Fatal nosocomial hemorrhagic enterocolitis probably caused by adenovirus. Report of one case
Título según SCIELO: Fatal nosocomial hemorrhagic enterocolitis probably caused by adenovirus. Report of one case
Título de la Revista: REVISTA MEDICA DE CHILE
Volumen: 147
Número: 2
Editorial: SOC MEDICA SANTIAGO
Fecha de publicación: 2019
Página de inicio: 256
Página final: 260
Idioma: English
DOI:

10.4067/s0034-98872019000200256

Notas: ISI, SCIELO, SCOPUS