Physiological and radio-induced modulations of low-weight globulins in distinct vascular compartments

Lima, Celso Vieira; Montano Valencia, Carlos Julio; Almeida, Iassudara Garcia

Abstract

The main goal was to investigate the profiles of molecular weight globulins lower than albumin in the electrophoresis system in function of the exposition time to gamma radiation. At 72h post-irradiation, the globulin electrophoretic profiles bellow albumin showed significant radio-induced changes. In addition, the vascular system, specifically the inferior vena cava, kidney, spleen, jugular, hepatic, and pulmonary veins presented a physiological compartmental distribution of globulins. The findings pointed out the radio-induced alterations of the serum globulin concentrations as a late event, possibly related to a radio modulation of the genes' expression.

Más información

Título según WOS: ID WOS:000447387400054 Not found in local WOS DB
Título de la Revista: JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
Volumen: 318
Número: 2
Editorial: Springer
Fecha de publicación: 2018
Página de inicio: 1317
Página final: 1324
DOI:

10.1007/s10967-018-6188-3

Notas: ISI