Abstract

Obesity is a major public health problem, both globally and particularly in our country. Therefore, all the studies that allow to under- stand the biological mechanisms related to the aetiology and development of obesity are of clinical and economic interest. In this study, we analysed some of the properties of a product based on Pinus radiata seed oil (SupD) and its effect on visceral adipose tissue patches in relation to the decrease in weight gain observed in a murine model of obesity. Our results suggest that the consumption of SupD promotes the hyperplastic growth of small adipocytes, increased vascularization in the visceral adipose tissue and favours a local anti-inflammatory environment. These observations are in agreement with the systemic metabolic effects observed in vivo, suggesting