Morphological evolution of the vertebrate forebrain: From mechanical to cellular processes

Aboitiz, Francisco; Montiel, Juan F.

Abstract

Although the cerebral hemispheres are among the defining characters of vertebrates, each vertebrate class is characterized by a different anatomical organization of this structure, which has become highly problematic for comparative neurobiology. In this article, we discuss some mechanisms involved in the generation of this morphological divergence, based on simple spatial constraints for neurogenesis and mechanical forces generated by increasing neuronal numbers during development, and the different cellular strategies used by each group to overcome these limitations. We expect this view to contribute to unify the diverging vertebrate brain morphologies into general, simple mechanisms that help to establish homologies across groups.

Más información

Título según WOS: Morphological evolution of the vertebrate forebrain: From mechanical to cellular processes
Título según SCOPUS: Morphological evolution of the vertebrate forebrain: From mechanical to cellular processes
Título de la Revista: EVOLUTION & DEVELOPMENT
Volumen: 21
Número: 6
Editorial: Wiley
Fecha de publicación: 2019
Página de inicio: 330
Página final: 341
Idioma: English
DOI:

10.1111/ede.12308

Notas: ISI, SCOPUS - ISI