Frequency of cervical cytological alterations and human papilloma virus in a sample of university students in Temuco, Chile

Angélica Melo; Sonia Montenegro; Sandra Liempi; Sergio Moreno; Tiare de-La-Barra; Pablo Guzmán; Luis Bustos; Flery Fonseca-Salamanca

Keywords: sexual behavior, university students, human papilloma virus, young women, cervical cytology, papanicolaou, virus papiloma humano, Mujeres jóvenes, citología cervical, estudiante universitaria, conductas sexuales

Abstract

Background: The early onset of sexual activity can promote the development of cervical alterations and sexually transmitted infections, especially the human papillomavirus (HPV) very common in adolescents and young people. Aim: The condition of the cervix, HPV and sexual behavior in young women under 25 years of age were analyzed. Methods: 182 university students, healthy, sexually active. 18-24 years old, without vaccine for HPV participated. Papanicolaou (Pap) test and classification of high and low risk HPV (HR and LR) were performed by real time polymerase chain reaction. The sexual behaviors were consulted in private. Results: The 46.9% of Pap presented cytological alterations, non-specific inflammation/hemorrhagic (29.4%) and atypical smear (10.2%) being de most frequent. The overall frequency of HPV-HR was 24.3%, of these 67.4% presented an altered Pap. There was an association between cytological alterations and HPV (p < 0.0001) and years of sexual activity and atypical smear or cervical intraepithelial neoplasia grade I (CIN I) (p = 0.009). 11.9% of young women (21/177) presented atypical smear or CIN I, with 66.7% of cases I-IPV-HR. Conclusions: These findings alert the vulnerability of these young women who would have a potential risk of viral persistence, CIN and eventually cancer. It is important to emphasize counseling and prevention prior to the regular age of admission to the screening program for cervical cancer. This study was financed by the Universidad de La Frontera through Projects DI15-0047 and DI17-0123.

Más información

Título según WOS: Frequency of cervical cytological alterations and human papilloma virus in a sample of university students in Temuco, Chile
Título según SCOPUS: Frequency of cervical cytological alterations and human papilloma virus in a sample of university students in Temuco, Chile [Frecuencia de alteraciones citológicas cervicales y virus papiloma humano en una muestra de estudiantes universitarias en Temuco, Chile]
Título según SCIELO: Frecuencia de alteraciones citológicas cervicales y virus papiloma humano en una muestra de estudiantes universitarias en Temuco, Chile
Título de la Revista: REVISTA CHILENA DE INFECTOLOGIA
Volumen: 36
Número: 4
Editorial: SOC CHILENA INFECTOLOGIA
Fecha de publicación: 2019
Página de inicio: 421
Página final: 427
Idioma: Spanish
DOI:

10.4067/S0716-10182019000400421

Notas: ISI, SCIELO, SCOPUS