Alternative polydenylation and the regulation of male germ cell differentiation

Fuller, Margaret; Olivares G.H.

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Fecha de publicación: 2014
Objetivos: The long-term goal of this project is to discover gene regulatory mechanisms that control the differentiation of male gametes, critical for understanding the genetic and molecular basis of male infertility.
Programa: Exploratory/Developmental Grants (R21)
Año de Inicio/Término: 2014-2016
Financiamiento/Sponsor: National Institute of Health (NIH)
Rol del Usuario: Postdoc
URL: https://grantome.com/grant/NIH/R21-HD079970-01A1
DOI:

1R21HD079970-01A1

Notas: The results of the proposed studies will reveal how a novel mode of gene regulation, developmentally controlled shortening of the 3'tails of transcripts, regulates expression of sets of proteins at specific stages of germ cell differentiation during spermatogenesis. The mechanisms we discover will p