Extension of surgical treatment and adjuvant chemotherapy in patients with incidental gallbladder cancer

Manterola C.; Grande L.; Otzen T.; Conejeros R.

Abstract

Objective: To describe the results of the extension of surgical treatment and adjuvant chemotherapy (ACT) in incidental gallbladder cancer (CVB), in terms of postoperative morbidity (POM) and 5-year overall survival rate. Method: Case series of patients operated on for incidental GBC in Clinica Mayor, Temuco, Chile (2001-2016). All cases were treated by partial hepatectomy (segments 1Vb and V), and regional lymphadenectomy. The minimum follow-up time was 12 months. Outcome variables were MPO and 5-year overall survival rate. Other variables of interest were: infiltration depth in vesicular wall, lymph nodes and resected liver; surgical time, need for reoperation, hospital stay, follow-up and mortality. Descriptive statistics were applied as well as bivariate analysis applying Fisher's exact and t-test and non-parametrical tests for continuous variables and Kaplan Meier curves. Results: The series was composed of 50 patients, whose average age was 58.6 +/- 9.6 years; 68.0% of which were women. The mean surgical time and hospital stay were 224 +/- 93 min (90 to 480) and 6.9 +/- 2.9 days (4 to 20), respectively. POM was 28.0%. 5-year overall survival rate was 47%. There were no reoperations or mortality. Conclusions: The results verified in terms of POM and 5-year overall survival rate are similar to previously reported series.

Más información

Título según WOS: Extension of surgical treatment and adjuvant chemotherapy in patients with incidental gallbladder cancer
Título según SCOPUS: Extension of surgical treatment and adjuvant chemotherapy in patients with incidental gallbladder cancer [Extensión del tratamiento quirúrgico y quimioterapia adyuvante en pacientes con carcinoma incidental de la vesícula biliar]
Título de la Revista: CIRUGIA Y CIRUJANOS
Volumen: 87
Número: 3
Editorial: MEXICAN ACAD SURGERY
Fecha de publicación: 2019
Página de inicio: 313
Página final: 320
Idioma: Spanish
DOI:

10.24875/CIRU.18000596

Notas: ISI, SCOPUS