Abstract

This work proposes a correlation methodology for solubilities (w(i)) of alpha-tocopherol and delta-tocopherol in supercritical CO2, and reports new experimental data at (40, 50, 60) degrees C and (9.8-33.6) MPa. The methodology is based on the Gibbs-Duhem test to assess thermodynamic consistency of isothermal solubilities, represented using the Peng-Robinson EoS + Wong-Sandler mixing rule. Chrastil's model was best-fitted after discarding low-solubility outlier (non-represented by the EoS), high-solubility (>100 g/m(3) solute/CO2, CO2 density modified by the solute), and thermodynamically inconsistent data. Additionally, the mean error of log(w(i)) (with thresholds for data reported of +/- 0.21 for alpha-tocopherol, and +/- 0.27 for delta-tocopherol) and the average bias were computed to discard questionable data sources. alpha-Tocopherol solubility was 3-to-4 times lower than delta-tocopherol's at equivalent system conditions. Their solubilities exhibited less dependency on system temperature and CO2 density than reported in literature, possibly due to experimental difficulties in handling comparably high-solubility solutes (>0.5 x 10(-3) mol/mol). (C) 2019 Elsevier B.V. All rights reserved.