An efficient and eco-friendly method for the thiol-Michael addition in aqueous solutions using amino acid ionic liquids (AAILs) as organocatalysts

Figueroa Guíñez, Roberto; Santos, José G.; Ricardo A. Tapia; Alcazar, Jackson J.; Aliaga, Margarita E.; Pavez, Paulina

Keywords: michael addition

Abstract

A series of amino-acid based ionic liquids (Bmim[AA]s) have been synthesized and evaluated as catalysts, in aqueous solution. The results of a kinetic study of the thiol-Michael reaction of L-Cysteine with trans-β-nitrostyrene demonstrated the advantages of using (Bmim[AA]s) as organocatalysts. The benefits include high rate constants; mild reaction conditions; and, a reusable catalyst, which leads to a simple and efficient method for these important kinds of reactions

Más información

Título de la Revista: PURE AND APPLIED CHEMISTRY
Volumen: 92
Editorial: De Gruyter
Fecha de publicación: 2020
Página de inicio: 97
Página final: 106
Idioma: english
DOI:

10.1515/PAC-2019-0212

Notas: ISI