Abstract

This article reviews ethical issues related to genome editing using CRISPR/Cas9 system. The use of CRISPR/cas9 revives many previous social and ethical issues with humans, other organisms and the environment, such astaking into account the non-maleficence principle in risk assessment, genome editing in germline, safety issues toavoid ecological impairment or the possible use of the technique for genetic enhancement. The new issue is therelatively simple construction and low cost of CRISPR/Cas9 for genome editing, with the possibility of multiplepurposes. A public dialogue over the social, ethical and legal implications with the regulatory needs of the system isnecessary.