Characterization of the antifungal activity on Botrytis cinerea of the natural diterpenoids kaurenoic acid and 3 beta-hydroxy-kaurenoic acid

Cotoras, M.; Folch, C.; Mendoza L.

Abstract

The antifungal activity on Botrytis cinerea of the diterpenoids 3?-hydroxy-kaurenoic acid and kaurenoic acid, obtained from the resinous exudates of Pseudognaphalium vira vira, was determined. 3? -Hydroxy-kaurenoic acid reduced the mycelial growth of B. cinerea in solid and liquid media. Additionally, the damage produced by the fungus on the surface of tomato leaves in the presence of the diterpenoids was evaluated. A higher protective effect was observed in the presence of the hydroxylated diterpene. On the other hand, the effect of the diterpenoids on the production of enzymes that participate in the plant infection by B. cinerea was analyzed. p-Nitrophenylbutyrate esterase production was induced by both diterpenoids, whereas laccase production was only induced by the hydroxylated diterpene. In the study of the mechanism of action of these compounds, it was determined that 3?-hydroxy-kaurenoic acid would produce permeabilization of the cell membrane of B. cinerea.

Más información

Título según WOS: Characterization of the antifungal activity on Botrytis cinerea of the natural diterpenoids kaurenoic acid and 3 beta-hydroxy-kaurenoic acid
Título según SCOPUS: Characterization of the Antifungal Activity on Botrytis cinerea of the Natural Diterpenoids Kaurenoic Acid and 3?-Hydroxy-kaurenoic Acid
Título de la Revista: JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Volumen: 52
Número: 10
Editorial: American Chemical Society
Fecha de publicación: 2004
Página de inicio: 2821
Página final: 2826
Idioma: English
DOI:

10.1021/jf030672j

Notas: ISI, SCOPUS