Synthesis of 9-and 10-membered macrolactones by selective ozonolysis of 1,4-diazaphenanthrene derivatives

Perez-Sacau, E; Soto-Delgado, J; Estevez-Braun, A; Ravelo, AG

Abstract

9- and 10-membered macrolactones bearing benzo and diazine rings were obtained by chemoselective ozonolysis of dihydrofuran and pyran 1,4-diazaphenathrene derivatives. This is the first example of preparation of macrolactones by chemoselective ozonolysis of an enol double bond shared by aromatic and heterocyclic rings. (C) 2004 Elsevier Ltd. All rights reserved.

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Título según WOS: ID WOS:000226332300014 Not found in local WOS DB
Título de la Revista: TETRAHEDRON
Volumen: 61
Número: 2
Editorial: PERGAMON-ELSEVIER SCIENCE LTD
Fecha de publicación: 2005
Página de inicio: 437
Página final: 445
DOI:

10.1016/j.tet.2004.10.075

Notas: ISI