Geographical distribution of genetic variants and lineages of SARS-CoV-2 in Chile

Andres E. Castillo1 , Barbara Parra1 , Paz Tapia1 , Jaime Lagos1 , Loredana Arata1 , Alejandra Acevedo2 , Winston Andrade2 , Gabriel Leal2 , Carolina Tambley2 , Patricia Bustos2 , Rodrigo Fasce2 , Jorge Fernández1*

Keywords: COVID-19, SARS-CoV- 2, Epidemiology, variants, Lineages

Abstract

The pandemic caused by the new coronavirus SARS-CoV-2 is a worldwide public health concern. First confined in China, and then disseminated widely across Europe and America, has impacted and moved the scientific community around the world to working in a fast and coordinated way to collect all possible information about this virus and generate new strategies and protocols to try to stop the infection. By now, more than 16,000 full viral genomes have been shared in public databases, that allows to construct genetic landscapes to try to track and monitoring the viral advances, and study the genomic variations presents in geographic regions and track the progress of the virus over time. In this work we present the occurrence of genetics variants and lineages of SARS-CoV-2 in Chile during March 2020. Complete genome analysis of 141 viral samples from different regions of Chile, revealed a predominance of variant G like in Europe and USA and the majority presence of lineage B.1. These findings could help to take control measures due the similarity of the viral variants present in Chile, compared with other countries, and the monitoring of the mutation rate of the virus in the territory.

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Fecha de publicación: 2020
Idioma: ingles
Notas: Submitted to Journal: Frontiers in Public Health Specialty Section: Infectious Diseases – Surveillance, Prevention and Treatment Article type:Brief Research Report Article Received on: 15 May 2020