Unwebbing the presynaptic web

Zamorano, PL; Garner, CC

Abstract

The release of neurotransmitter from nerve terminals occurs at a specialized region of the presynaptic plasma membrane called the active zone. A dense matrix of proteins associated with the active zone, called the presynaptic web, is thought to play a fundamental role in defining these neurotransmitter release sites. In this issue of Neuron, Phillips et al. have identified conditions for the biochemical purification of the presynaptic web and show that the web is comprised of proteins involved in the docking, fusion, and recycling of synaptic vesicles.

Más información

Título según WOS: ID WOS:000171525200002 Not found in local WOS DB
Título de la Revista: NEURON
Volumen: 32
Número: 1
Editorial: Cell Press
Fecha de publicación: 2001
Página de inicio: 3
Página final: 6
DOI:

10.1016/S0896-6273(01)00458-5

Notas: ISI