Article ISI
TETRAHEDRON-ASYMMETRY  (2013)

Synthesis of enantiopure beta(2)-homoalanine derivatives via rhodium catalyzed asymmetric hydrogenation

Luehr, Susan; Holz, Jens; Zayas, Odalys; Seidelmann, Oliver; Domke, Lutz; Boerner, Armin

Abstract

The stereoselective synthesis of chiral beta(2)-homoalanine derivatives with 99% ee by the Rh-catalyzed enantioselective hydrogenation of prochiral 2-aminomethyl acrylates is described. The subsequent transformation to chiral 3-amino-2-methylpropanols is also demonstrated. (c) 2013 Elsevier Ltd. All rights reserved.

Más información

Título según WOS: ID WOS:000318209700007 Not found in local WOS DB
Título de la Revista: TETRAHEDRON-ASYMMETRY
Volumen: 24
Número: 7
Editorial: PERGAMON-ELSEVIER SCIENCE LTD
Fecha de publicación: 2013
Página de inicio: 395
Página final: 401
DOI:

10.1016/j.tetasy.2013.02.011
Notas: ISI