Abstract

Epithelial-myoepithelial carcinoma (EMC) is a rare salivary gland neoplasm with an incidence of less than 1%. It tends to form biphasic ductal structures, consisting of epithelial cells lining the lumen which is surrounded by abluminal myoepithelial cells. Occasionally, EMC may show a predominance of clear myoepithelial cells. In this report involving a 64-year-old woman, we describe a case of EMC of the right parotid gland with a less obvious biphasic pattern, and importantly, a double clear cell component, showing development of clear myoepithelial cells inside and outside of the lumen. Our objective is to demonstrate the importance of immunohistochemistry in identifying this tumour when faced with the differential diagnoses of clear cell tumours.