Abstract

Background: Use of cadaveric cryopreserved saphenous vein grafts (CSVGs) has been described for peripheral vascular and coronary re-vascularization. The aim of this study is to recognize CSVGs as a potential alternative to autologous conduits for extracranial-intracranial (EC-IC) bypass in patients without available or suitable saphenous vein graft or radial artery. We report the short-term patency rate of CSVGs in EC-IC bypass. Methods: We present our preliminary experience in 10 patients using CSVG for cerebral revascularization. Data regarding operative indications, patient demographics, and bypass patency were collected. Results: The average age was 56 years old with equal sex distribution. The indications for the procedure were giant aneurysms in 7 patients, medically refractory vertebrobasilar ischemia in 2, and a skull base tumor in 1. ABO/Rh blood group compatible CSVG was used in each case. Postoperative angiography demonstrated patency in all cases. Quantitative magnetic resonance angiography was performed in 8 patients, demonstrating a mean bypass flow of 109 mL/min +/- 19 mL/min (mean +/- SE). Conclusions: Use of CSVG for EC-IC bypass has not previously been reported. In our series, the short-term patency rate was 100%, better than that found in cardiac and peripheral vascular series, possibly because of the higher flow in EC-IC bypasses. Our preliminary experience suggests that CSVGs may be an option in patients without available autologous conduits, although longer follow-up is needed to assess long-term patency. (C) 2009 Elsevier Inc. All rights reserved.