PRODUCTION OF REFERENCE MATERIAL FOR THE DETECTION AND QUANTIFICATION OF DINOPHYSISTONIN-3 TOXIN, A DERIVATIVE OF DINOPHYSISTONIN-1, THE MOST POTENT DIARRHETIC TOXIN. PURIFICATION FROM CONTAMINATED SHELLFISH.
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Fecha de publicación: | 2009 |
Objetivos: | To identify, quantitate and purify Dinophysistoxin-3 (DTX-3, 7-O-acyl-Dinophysistoxin-1) starting from contaminated mollusks (1 to 2 tons) as raw material and to develop a routinary biochemical purification procedure for this toxin. |
Instrumento: | FONDECYT |
Año de Inicio/Término: | 2009-2012 |
Financiamiento/Sponsor: | CONICYT |
Rol del Usuario: | INVESTIGADOR(A) RESPONSABLE |
URL: | http://repositorio.conicyt.cl/handle/10533/120697 |
DOI: |
1090058 |
Notas: | Diarrheic Shellfish Poison (DSP) is associated to the most widely distributed marine toxin related syndrome across the world. It was described in Japan, after a 1976 massive intoxication caused by ingestion of DSP contaminated mollusks. Main symptoms of this syndrome are: diarrhea, nausea (80%) |