Article ISI
JOURNAL OF THE CHILEAN CHEMICAL SOCIETY  (2011)

SYNTHESIS OF 1-BENZYL-3-[4-(ARYL-1-PIPERAZINYL) CARBONYL]-1H-INDOLES. NOVEL LIGANDS WITH POTENTIAL D4 DOPAMINERGIC ACTIVITY

Pessoa-Mahana, Hernan; Cuevas, Ignacio M.; Pessoa-Mahana, David; Araya-Maturana, Ramiro; Fajardo, Iriux Almodovar; Barria, Claudio Saitz

Abstract

The synthesis of a series of functionalized 1-Benzyl-3[4-Aryl-1-piperazinyl]carbonyl-1H-Indoles 6(a-f), as a potential new class of bioactive ligands at D, receptors is reported. The synthetic strategy took place through a five steps sequence to provide indole amides 6(a-f) in 75-92% yield.

Más información

Título según WOS: SYNTHESIS OF 1-BENZYL-3-[4-(ARYL-1-PIPERAZINYL) CARBONYL]-1H-INDOLES. NOVEL LIGANDS WITH POTENTIAL D4 DOPAMINERGIC ACTIVITY
Título de la Revista: JOURNAL OF THE CHILEAN CHEMICAL SOCIETY
Volumen: 56
Número: 4
Editorial: 2013
Fecha de publicación: 2011
Página de inicio: 866
Página final: 869
DOI:

10.4067/S0717-97072011000400009
Notas: ISI