DNA hydroxymethylation in the T cell lineage: examining the role of the DNA hydroxylase Tet1 and hydroxymethylation in bookmarking key genes for function and development
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Fecha de publicación: | 2017 |
Objetivos: | (1) Investigate Tet1 binding at 5hmC bookmarked genes and identify its binding partners (2) Assess the role of Tet1 in cellular homeostasis, differentiation and on the preservation of 5hmC bookmarks (3) Identify readers of 5hmC with known roles in gene regulation |
Instrumento: | FONDECYT |
Año de Inicio/Término: | 2017-2021 |
Financiamiento/Sponsor: | CONICYT |
Rol del Usuario: | INVESTIGADOR(A) RESPONSABLE |
DOI: |
1171004 |