Mild and rapid method for the generation of o-quinone methide intermediates. Synthesis of puupehedione analogues
Abstract
A route to simpler analogues to bioactive puupehedione derivatives involving a hetero Diels-Alder cycloaddition of a o-quinone methide is described. These intermediate species are generated via fluoride-induced desilylation of silyl derivatives of o-hydroxybenzyl iodides. Remarkable short reaction times and very mild experimental conditions are the main features of this method. © 2006 Elsevier Ltd. All rights reserved.
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| Título según WOS: | Mild and rapid method for the generation of o-quinone methide intermediates. Synthesis of puupehedione analogues |
| Título según SCOPUS: | Mild and rapid method for the generation of o-quinone methide intermediates. Synthesis of puupehedione analogues |
| Título de la Revista: | TETRAHEDRON |
| Volumen: | 62 |
| Número: | 25 |
| Editorial: | PERGAMON-ELSEVIER SCIENCE LTD |
| Fecha de publicación: | 2006 |
| Página de inicio: | 6012 |
| Página final: | 6017 |
| Idioma: | English |
| URL: | http://linkinghub.elsevier.com/retrieve/pii/S0040402006005588 |
| DOI: |
10.1016/j.tet.2006.04.004 |
| Notas: | ISI, SCOPUS |