Mild and rapid method for the generation of o-quinone methide intermediates. Synthesis of puupehedione analogues
Abstract
A route to simpler analogues to bioactive puupehedione derivatives involving a hetero Diels-Alder cycloaddition of a o-quinone methide is described. These intermediate species are generated via fluoride-induced desilylation of silyl derivatives of o-hydroxybenzyl iodides. Remarkable short reaction times and very mild experimental conditions are the main features of this method. © 2006 Elsevier Ltd. All rights reserved.
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Título según WOS: | Mild and rapid method for the generation of o-quinone methide intermediates. Synthesis of puupehedione analogues |
Título según SCOPUS: | Mild and rapid method for the generation of o-quinone methide intermediates. Synthesis of puupehedione analogues |
Título de la Revista: | TETRAHEDRON |
Volumen: | 62 |
Número: | 25 |
Editorial: | PERGAMON-ELSEVIER SCIENCE LTD |
Fecha de publicación: | 2006 |
Página de inicio: | 6012 |
Página final: | 6017 |
Idioma: | English |
URL: | http://linkinghub.elsevier.com/retrieve/pii/S0040402006005588 |
DOI: |
10.1016/j.tet.2006.04.004 |
Notas: | ISI, SCOPUS |