Abstract

Segmentation of the Left Ventricle (LV) from MRI and 4D flow datasets is an essential step for quantifying clinical indices and hemodynamicparameters. Automatic methods for heart segmentation are generally validated using cardiac volumetric and global ejection fraction. However, littleis known about the changes of hemodynamic parameters when subjected to different segmentations. In this study, we present a sensitivityassessment of left intraventricular hemodynamic parameters in healthy volunteers and Dilated Cardiomyopathy (DCM) patients using a finite elementquantification approach using 4D flow MRI data, when subjected to changes of LV segmentations.