Development and validation of the first consensus gene-expression signature of operational tolerance in kidney transplantation, incorporating adjustment for immunosuppressive drug therapy

Taube, Catharine; Augustine, Titus; Griffi, Sian; Paz-Artal, Estela; Sinha, Manish D.; Viklick, Ondrej

Abstract

Background: Kidney transplant recipients (KTRs) with "operational tolerance" (OT) maintain a functioning graft without immunosuppressive (IS) drugs, thus avoiding treatment complications. Nevertheless, IS drugs can influence gene-expression signatures aiming to identify OT among treated KTRs.

Más información

Título según WOS: Development and validation of the first consensus gene-expression signature of operational tolerance in kidney transplantation, incorporating adjustment for immunosuppressive drug therapy
Título de la Revista: EBIOMEDICINE
Volumen: 58
Editorial: Elsevier
Fecha de publicación: 2020
DOI:

10.1016/J.EBIOM.2020.102899

Notas: ISI