Article ISI
ANNALS OF TRANSLATIONAL MEDICINE  (2020)

Differential expression of genes related to calcineurin and mTOR signaling and regulatory miRNAs in peripheral blood from kidney recipients under tacrolimus-based therapy

Bonezi, Vivian; Genvigir, Fabiana Dalla Vecchia; Salgado, Patricia de Cassia; Felipe, Claudia Rosso; Tedesco-Silva Jr, Helio; Medina-Pestana, Jose Osmar; Cerda, Alvaro; Doi, Sonia Quateli; Hirata, Mario Hiroyuki; Crespo Hirata, Rosario Dominguez

Abstract

Background: Genetic and epigenetics factors have been implicated in drug response, graft function and rejection in solid organ transplantation. Differential expression of genes involved in calcineurin and mTOR signaling pathway and regulatory miRNAs was analyzed in the peripheral blood of kidney recipient cohort (n=36) under tacrolimus-based therapy.

Más información

Título según WOS: Differential expression of genes related to calcineurin and mTOR signaling and regulatory miRNAs in peripheral blood from kidney recipients under tacrolimus-based therapy
Título de la Revista: ANNALS OF TRANSLATIONAL MEDICINE
Volumen: 8
Número: 17
Editorial: AME PUBL CO
Fecha de publicación: 2020
DOI:

10.21037/ATM-20-1757
Notas: ISI