Syndecan-4/PAR-3 signaling regulates focal adhesion dynamics in mesenchymal cells

Valdivia, Alejandra; Cardenas, Areli; Brenet, Marianne; Maldonado, Horacio; Kong, Milene; Diaz, Jorge; Burridge, Keith; Schneider, Pascal; San Martin, Alejandra; Garcia-Mata, Rafael; Quest, Andrew F. G.; Leyton, Lisette

Abstract

Background: Syndecans regulate cell migration thus having key roles in scarring and wound healing processes. Our previous results have shown that Thy-1/CD90 can engage both alpha v beta 3 integrin and Syndecan-4 expressed on the surface of astrocytes to induce cell migration. Despite a well-described role of Syndecan-4 during cell movement, information is scarce regarding specific Syndecan-4 partners involved in Thy-1/CD90-stimulated cell migration.

Más información

Título según WOS: Syndecan-4/PAR-3 signaling regulates focal adhesion dynamics in mesenchymal cells
Título de la Revista: CELL COMMUNICATION AND SIGNALING
Volumen: 18
Número: 1
Editorial: BMC
Fecha de publicación: 2020
DOI:

10.1186/S12964-020-00629-3

Notas: ISI