Article ISI SCOPUS
EUROPEAN JOURNAL OF MEDICAL GENETICS  (2006)

HLA non-class II genes may confer type I diabetes susceptibility in a mapuche (Amerindian) affected family

Perez-Bravo, F; Martinez-Laso, J; Martin-Villa, JM; Moscoso J.; Moreno A.; Serrano-Vela, JI; Zamora J.; Asenjo, S; gleisner a; Arnaiz-Villena, A

Abstract

A rare case of type I diabetes is studied in an Amerindian (Mapuche) family from Chile, analyzing glutamic acid decarboxylase, islet-cell autoantibodies and human leukocyte antigen (HLA) genes. The affected sib is the only one that has one specific HLA haplotype combination that differs from the other sibs only in the HLA class I genes. It is concluded that HLA diabetes susceptibility factors may be placed outside the class II region or even that susceptibility factors do not exist in the HLA region in this Amerindian family. © 2004 Elsevier SAS. All rights reserved.

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Título según WOS: HLA non-class II genes may confer type I diabetes susceptibility in a mapuche (Amerindian) affected family
Título según SCOPUS: HLA non-class II genes may confer type I diabetes susceptibility in a mapuche (Amerindian) affected family
Título de la Revista: EUROPEAN JOURNAL OF MEDICAL GENETICS
Volumen: 49
Número: 1
Editorial: ELSEVIER SCIENCE BV
Fecha de publicación: 2006
Página de inicio: 37
Página final: 41
Idioma: English
URL: http://linkinghub.elsevier.com/retrieve/pii/S1769721205000339
DOI:

10.1016/j.ejmg.2005.01.027
Notas: ISI, SCOPUS