Pneumocystis jirovecii colonization in preterm newborns with respiratory distress syndrome.

Szyd?owicz M, Królak-Olejnik B, Vargas SL, Zaj?czkowska ?, Paluszy?ska D, Szczygie? A, Matos O, Hendrich AB, Kicia M.

Abstract

We describe the prevalence of Pneumocystis jirovecii in mother-infant pairs of very low birth weight newborns <32 weeks gestation. Molecular and microscopic methods were used for detection of P. jirovecii in patients' specimens. Pneumocystis DNA was detected in eight nasopharyngeal aspirates (14%) of 56 newborns and in seven oral washes (21%) of 34 mothers. Pneumocystis detection immediately after birth suggests the possibility of its transplacental transmission. Comparing to non-colonized infants, more frequent occurrence of bronchopulmonary dysplasia was seen in colonized ones (P=0.02), suggesting a potential clinical importance of this pathogen in abnormal lung development.

Más información

Título de la Revista: JOURNAL OF INFECTIOUS DISEASES
Editorial: OXFORD UNIV PRESS INC
Fecha de publicación: 2021
Idioma: Inglés
URL: doi: 10.1093/infdis/jiab209.
DOI:

33857302

Notas: ISI, Scopus, Pubmed