Article ISI
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE  (2021)

Decreased caveolae in AGPAT2 lacking adipocytes is independent of changes in cholesterol or sphingolipid levels: A whole cell and plasma membrane lipidomic analysis of adipogenesis

Gonzalez-Hodar, Lila; McDonald, Jeffrey G.; Vale, Goncalo; Thompson, Bonne M.; Figueroa, Ana-Maria; Tapia, Pablo J.; Robledo, Fermin; Agarwal, Anil K.; Garg, Abhimanyu; Horton, Jay D.; Cortes, Victor

Abstract

Background: Adipocytes from lipodystrophic Agpat2(-/-) mice have impaired adipogenesis and fewer caveolae. Herein, we examined whether these defects are associated with changes in lipid composition or abnormal levels of caveolae-associated proteins. Lipidome changes were quantified in differentiated Agpat2(-/-) adipocytes to identify lipids with potential adipogenic roles.

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Título según WOS: Decreased caveolae in AGPAT2 lacking adipocytes is independent of changes in cholesterol or sphingolipid levels: A whole cell and plasma membrane lipidomic analysis of adipogenesis
Título de la Revista: BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
Volumen: 1867
Número: 9
Editorial: Elsevier
Fecha de publicación: 2021
DOI:

10.1016/J.BBADIS.2021.166167
Notas: ISI