Pharmacokinetics of a single oral dose of 1.5-mg levonorgestrel when administered as 750-mu g tablets or as 30-mu g minipills

Devoto L.; Espinoza, A.; MuÑoz A.; Fuentes, A.; von Hertzen, H

Abstract

We examined the pharmacokinetics of a single dose of 1.5 mg of levonorgestrel when administered orally in two different formulations: two tablets of 0.75 mg or 50 minipills of 30 μg of levonorgestrel. Bioavailability of levonorgestrel with minipills was comparable to that with levonorgestrel tablets. These findings suggest that levonorgestrel-containing minipills can be considered as an alternative to standard levonorgestrel tablets for use in emergency contraception. © 2007 American Society for Reproductive Medicine.

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Título según WOS: Pharmacokinetics of a single oral dose of 1.5-mg levonorgestrel when administered as 750-mu g tablets or as 30-mu g minipills
Título según SCOPUS: Pharmacokinetics of a single oral dose of 1.5-mg levonorgestrel when administered as 750-µg tablets or as 30-µg minipills
Título de la Revista: FERTILITY AND STERILITY
Volumen: 88
Número: 4
Editorial: Elsevier Science Inc.
Fecha de publicación: 2007
Página de inicio: 976
Página final: 977
Idioma: English
URL: http://linkinghub.elsevier.com/retrieve/pii/S0015028207000489
DOI:

10.1016/j.fertnstert.2006.12.088

Notas: ISI, SCOPUS