Clinic variation in glycaemic control for children with Type 1 diabetes in England and Wales: a population-based, multilevel analysis

Charalampopoulos, D.; Amin, R.; Warner, J. T.; Muniz-Terrera, G.; Paes, V. Mazarello; Viner, R. M.; Stephenson, T.

Abstract

Aim To understand the scope for improving children's glycaemic outcomes by reducing variation between clinics and examine the role of insulin regimen and clinic characteristics. Methods Cross-sectional analysis of 2012-2013 National Paediatric Diabetes Audit data from 21 773 children aged 19 years with Type 1 diabetes cared for at 176 clinics organized into 11 regional diabetes networks in England and Wales. Variation in HbA(1c) was explored by multilevel models with a random effect for clinic. The impact of clinic context was quantified by computing the per cent of total variation in HbA(1c) which occurs between clinics (intraclass correlation coefficient; ICC). Results Overall, 69 of the 176 diabetes clinics (39%) had a glycaemic performance that differed significantly from the national average after adjusting for patient case-mix with respect to age, gender, diabetes duration, deprivation and ethnicity. However, differences between clinics accounted for 4.7% of the total variation in HbA(1c). Inclusion of within-clinic HbA(1c) standard deviation led to a substantial reduction in ICC to 2.4%. Insulin regimen, clinic volume and diabetes networks had a small or moderate impact on ICC. Conclusions Differences between diabetes clinics accounted for only a small portion of the total variation in glycaemic control because most of the variation was within clinics. This implies that national glycaemic improvements might best be achieved not only by targeting poor centres but also by shifting the whole distribution of clinics to higher levels of quality.

Más información

Título según WOS: ID WOS:000415191800009 Not found in local WOS DB
Título de la Revista: DIABETIC MEDICINE
Volumen: 34
Número: 12
Editorial: Wiley
Fecha de publicación: 2017
Página de inicio: 1710
Página final: 1718
DOI:

10.1111/dme.13442

Notas: ISI