Article ISI
PHARMACOLOGICAL REPORTS  (2021)

Effect of statins on lipid metabolism-related microRNA expression in HepG2 cells

Cerda, Alvaro; Bortolin, Raul Hernandes; Manriquez, Victor; Salazar, Luis; Zambrano, Tomas; Fajardo, Cristina Moreno; Hirata, Mario Hiroyuki; Hirata, Rosario Dominguez Crespo

Abstract

Background Statins are potent cholesterol-lowering drugs that prevent cardiovascular events. microRNAs (miRNAs) modulate the expression of genes involved in metabolic pathways and cardiovascular functions post-transcriptionally. This study explored the effects of statins on the expression of miRNAs and their target genes involved in lipid metabolism in HepG2 cells.

Más información

Título según WOS: Effect of statins on lipid metabolism-related microRNA expression in HepG2 cells
Título de la Revista: PHARMACOLOGICAL REPORTS
Volumen: 73
Número: 3
Editorial: SPRINGER HEIDELBERG
Fecha de publicación: 2021
Página de inicio: 868
Página final: 880
DOI:

10.1007/S43440-021-00241-3
Notas: ISI