Proyecto
 (2022)

Role of ACE2 and angiotensin-(1-9) in the development of heart failure with preserved ejection fraction in mice

Ocaranza-Jeraldino María Paz; Garrido M, Cárdenas AM, Astorga J, Quinlan F, Valdés M, Chaparro A, Carvajal P, Pussinen P, Huamán-Chipana P, Jalil JE, Hernández M.; Gabrielli L.A.; Hermoso R, Marcela

Más información

Fecha de publicación: 2022
Objetivos: Aim 1: To assess the ACE/Ang II and ACE2/Ang-(1–9) axes in an experimental HFpEF mouse model (high-fat diet plus L-NAME) throughout the progression of HFpEF.Aim 2: To determine macrophage phenotype in cardiac tissue in an experimental HFpEF mouse model (high-fat diet plus L-NAME) throughout ...
Instrumento: FONDECYT
Año de Inicio/Término: 2022-2025
Financiamiento/Sponsor: CONICYT
Rol del Usuario: INVESTIGADOR(A) RESPONSABLE
DOI:

1221585
Notas: the progression of HFpEF. Aim 3: To study the participation of ACE2 and Ang-(1–9) in cardiac macrophage phenotype and myocardial remodeling and function throughout the progression of HFpEF in a mouse model (high-fat diet plus L-NAME).