Abstract

Haemodynamics plays an important role in the progression and rupture of cerebral aneurysms. The temporal and spatial variations of the wall shear stress in the aneurysmal sac are hypothesized to be correlated with its growth and rupture. In addition, the assessment of the velocity field in the aneurysm dome and neck is important for the correct placement of endovascular coils. This work describes the flow dynamics in patient-specific models of saccular aneurysms of different sizes located in the ophthalmic artery. The models were obtained from three-dimensional rotational angiography image data and blood flow dynamics was studied under physiologically representative waveform of inflow. The three-dimensional continuity and momentum equations for unsteady laminar flow were solved with commercial software using nonstructured fine grid sizes. The intra-aneurysmal flows show complex vortex structures that change during one pulsatile cycle. A relation between the aneurysm aspect ratio and the mean wall shear stress on the aneurysmal sac is showed. Copyright © 2006 John Wiley & Sons, Ltd.