Article ISI
CRITICAL CARE  (2022)

Sildenafil for treating patients with COVID-19 and perfusion mismatch: a pilot randomized trial

Gutierrez Claveria, Monica; Vidal Marambio, Jaime; Retamal Baez, Nicole; Pavez Novoa, Cristian; Reyes Allende, Cesar; Ferreira Perey, Paulina; Gutierrez Torres, Miguel; Villalobos Mazza, Camila; Vergara Sagredo, Constanza; Ahumada Bermejo, Sebastian; Labarca Mellado, Eduardo; Barthel Munchmeyer, Elizabeth; Marchant Ramos, Solange; Vega, Jorge

Abstract

Background: SARS-CoV-2 seems to affect the regulation of pulmonary perfusion. Hypoperfusion in areas of well-aerated lung parenchyma results in a ventilation-perfusion mismatch that can be characterized using subtraction computed tomography angiography (sCTA). This study aims to evaluate the efficacy of oral sildenafil in treating COVID-19 inpatients showing perfusion abnormalities in sCTA.

Más información

Título según WOS: Sildenafil for treating patients with COVID-19 and perfusion mismatch: a pilot randomized trial
Título de la Revista: CRITICAL CARE
Volumen: 26
Número: 1
Editorial: LONDON
Fecha de publicación: 2022
DOI:

10.1186/S13054-021-03885-Y
Notas: ISI